BRD 8430 ( BRD8430 )

Catalog No. M12045 CAS No. 1482499-16-0

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Datasheet

HNMR

HPLC

MSDS

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Product Name

BRD 8430
Note

Research use only, not for human use.
Brief Description

BRD 8430 is a potent, selective class I HDAC inhibitor (HDAC1>2 >3) with IC50 of 69 nM/560/1300 nM for HDAC1/2/3, respectively.
Description

BRD 8430 is a potent, selective class I HDAC inhibitor (HDAC1>2 >3) with IC50 of 69 nM/560/1300 nM for HDAC1/2/3, respectively; shows no activity against other HDACs; decreases viability and induces differentiation of neuroblastoma cell lines.
Synonyms

BRD8430
Pathway

Cell Cycle/DNA Damage
Target

HDAC
Recptor

HDAC
Research Area

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Indication

——

CAS Number

1482499-16-0
Formula Weight

573.74
Molecular Formula

C33H43N5O4
Purity

>98% (HPLC)
Solubility

——
SMILES

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Chemical Name

N-(2-aminophenyl)-4-[[[(2R,3S)-9-(dimethylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-2-yl]methyl-methylamino]methyl]benzamide

1. Frumm SM, et al. Chem Biol. 2013 May 23;20(5):713-25.

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